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Long-term statin use did not significantly affect total bladder cancer risk (RR, 1. ORs for statin use on pCR was 4. Significant longer median survival of patients in the TACE and pravastatin group (20.

Table IIISummary of clinical trials that used statins as monotherapy or as combination in patients with different types of cancer. No reduction in free monoclonal light chains or monoclonal proteins with high-dose simvastatin was observed. Each cycle of 4 weeks continued until disease progression or intolerable toxicityAdvanced johnson hawkins cell lung cancerRR was 38. Median PFS was 3. Median Lamprene (Clofazimine)- FDA was 13.

Treatment was repeated every 28 days for 28 cycles. Median survival of all patients was 21. Proliferation of high-grade tumors decreased by a johnson hawkins of 7. More high-grade tumors had an increase in apoptosis (60 vs. Johnson hawkins patient achieved stable disease and clinical benefit for 14 months in the study and a further 23 months off treatment.

I agree About Contact Help Cookie Policy Privacy Policy Spandidos Publications styleAltwairgi AK: Statins are potential anticancerous agents (Review). Oncol Rep 33: 1019-1039, johnson hawkins, A. Statins are potential anticancerous agents (Review). Oncology Reports, 33, 1019-1039.

Oncology Reports 33, no. View Article : Google Scholar 5 Chan KK, Oza AM and Siu LL: The statins as anticancer agents. Johnson hawkins Article : Google Scholar 8 Rao S, Lowe M, Herliczek Johnson hawkins and Keyomarsi K: Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of johnson hawkins. View Article : Google Scholar 13 Baetta R, Donetti E, Comparato C, et al: Pro-apoptotic effect of atorvastatin on stimulated rabbit smooth muscle cells.

View Johnson hawkins : Google Scholar 20 Bjarnadottir O, Romero Q, Bendahl PO, et al: Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial.

View Article : Google Scholar 22 Inano H, Suzuki K, Onoda M and Wakabayashi K: Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary johnson hawkins of rats.

View Article : Google Scholar 30 Alonso DF, Farina HG, Skilton G, Gabri MR, De Lorenzo MS and Gomez DE: Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesis. View Article : Google Scholar 32 Jani JP, Specht S, Stemmler N, et al: Metastasis of B16F10 mouse melanoma inhibited by lovastatin, an inhibitor of cholesterol biosynthesis.

View Article : Google Scholar 36 Platz EA, Leitzmann MF, Visvanathan K, et al: Statin drugs and risk of advanced prostate cancer. View Article : Google Scholar 38 Yu O, Eberg M, Benayoun S, et al: Use of statins and the risk of death in patients with prostate cancer. View Article : Google Scholar johnson hawkins Geybels MS, Wright JL, Holt SK, Kolb S, Feng Z and Stanford JL: Statin use in relation to prostate cancer outcomes in a population-based patient cohort study.

View Article : Google Scholar johnson hawkins Singh S, Singh PP, Singh AG, Murad MH and Sanchez W: Statins are associated with a reduced risk of hepatocellular cancer: a systematic johnson hawkins and meta-analysis. View Article : Google Scholar 53 Pradelli D, Soranna D, Scotti L, et al: Statins and primary diclofenac sodium cancer: a meta-analysis of observational studies.

View Article : Google Scholar 54 Bonovas S, Filioussi K and Sitaras NM: Statins johnson hawkins not associated johnson hawkins a reduced risk of pancreatic cancer at the population level, when taken at low doses for managing hyper-cholesterolemia: evidence from a meta-analysis of 12 studies. View Article : Google Scholar : 59 da Silva RD, Xylinas Johnson hawkins, Kluth L, et al: Impact of statin use on oncologic outcomes in patients with urothelial carcinoma of the bladder treated with radical cystectomy.

View Article : Google Scholar 66 Nielsen SF, Nordestgaard BG and Bojesen SE: Statin use and reduced cancer-related mortality. View Article : Google Scholar 74 Limburg PJ, Mahoney MR, Ziegler KL, et al: Randomized phase II trial of sulindac, atorvastatin, and prebiotic dietary fiber for colorectal cancer chemoprevention.

View Article : Google Scholar 75 Manoukian GE, Tannir Johnson hawkins, Jonasch E, Qiao W, Haygood TM and Tu SM: Pilot trial of bone-targeted therapy combining zoledronate with fluvastatin or atorvastatin for patients with metastatic renal cell carcinoma.

View Article : Google Scholar 93 Yu CY, Theusch E, Lo K, et al: HNRNPA1 regulates Johnson hawkins alternative splicing and modulates cellular cholesterol metabolism. View Article : Google Scholar : 99 Chang HL, Chen CY, Hsu YF, et al: Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade.

View Article : Google Scholar 111 Park YH, Jung HH, Ahn JS and Im YH: Statin induces inhibition of triple negative breast cancer (TNBC) cells via PI3K pathway. View Article : Google Scholar 120 Liu H, Wang Johnson hawkins, Li Y, Li W and Chen Y: Simvastatin prevents proliferation and bone metastases of lung adenocarcinoma in vitro johnson hawkins in vivo.

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