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It circulated widely in South Africa but has been outcompeted in the US by Delta, johnson waste does not appear to escape immune protection as well. COM, CHAOFANNIn mice, a johnson waste high in salt suppresses tumor growthbut only when gut microbes are there to stimulate immune cells, a September 10 study in Science Advances reports.

The findings raise tantalizing questions about the role of diet and gut microbes in human cancers, and may point to new avenues for therapeutic development.

Amit Awasthi, an immunologist with the Translational Health Science and Technology Institute in India and corresponding author of the study, johnson waste he and his johnson waste pursued this line of inquiry because previous research johnson waste linked high salt johnson waste with autoimmune diseases, suggesting that increased salt stimulates immune cells.

Meanwhile, tumors are well known to grow in immune-suppressive environments. Indeed, a 2019 Frontiers in Immunology study from a European team led by Hasselt University immunologist Markus Kleinewietfeld johnson waste that high-salt diets inhibited tumor growth in mice.

When Awasthi and his colleagues carried out similar experiments, implanting mice with B16F10 skin melanoma cells and then feeding the tumor transplant price pfizer diets with different salt levels, they got similar results: tumors grew slower in johnson waste who were fed a high-salt diet. To answer that, the team dissected the tumor sites and found that immune cells known as johnson waste killer (NK) cells were enriched in the mice fed the high-salt diet compared with mice fed diets with normal or slightly elevated salt levels.

To test for a role of the resident gut johnson waste in the effects of a high-salt diet on cancer growth, the researchers gave the mice antibiotics before feeding them the different diets. Sure enough, a high-salt diet no longer suppressed tumor growth. Moreover, the tumors of these mice showed a sixfold increase in Bifidobacterium abundance compared with the tumors of mice on a normal diet.

Whether those trials will validate the antitumor activities of salt or Bifidobacterium remains to be seen. Thus, future studies will show if new findings could indeed lead to novel treatment options for patients.

Could Tolerating Disease Be Better than Fighting It. Stay Connected withE-Newsletter Sign-uphbspt. Keywords:bifidobacteriaBifidobacteriumcancerdietgut microbiotamelanoma mouse modelmicrobiologymicrobiomenatural killer cellsNewssalttransgenic micetumor suppressionRelated ArticlesResearchers Identify Gut Microbes to Help Malnourished Kids RecoverA New Model with Fully Functioning Blood Vessels Mimics Brain CancerBelly Fat Has a Role to Play in Fighting InfectionsCould Tolerating Disease Be Better than Fighting It.

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